Caffeine Anhydrous

Our Products with Caffeine Anhydrous in them. 

This information is from Webmd.com

OTHER NAME(S): 1,3,7-Trimethyl-1H-purine- 2,6(3H,7H)-dione, 1,3,7-trimethylxanthine, 1,3,7-triméthylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione, Anhydrous Caffeine, Cafeina, Caféine, Caféine Anhydre, Caféine Benzodate de Sodium, Caffeine Sodium Benzoate, Caffeine Anhydrous, Caffeine Citrate, Caffeinum, Citrate de Caféine, Citrated Caffeine, Methylxanthine, Méthylxanthine, Trimethylxanthine, Triméthylxanthine.

Overview Information

Caffeine is a chemical found in coffee, tea, cola, guarana, mate, and other products.
Caffeine is most commonly used to improve mental alertness, but it has many other uses. Caffeine is used by mouth or rectally in combination with painkillers (such as aspirin and acetaminophen) and a chemical called ergotamine for treating migraine headaches. It is also used with painkillers for simple headaches and preventing and treating headaches after epidural anesthesia.
Some people use caffeine by mouth for asthma, gallbladder disease, attention deficit-hyperactivity disorder (ADHD), and many other conditions, but there is no good scientific evidence to support most of these uses.
Caffeine is one of the most commonly used stimulants among athletes. Taking caffeine, within limits, is allowed by the National Collegiate Athletic Association (NCAA). Urine concentrations over 15 mcg/mL are prohibited. It takes most people about 8 cups of coffee providing 100 mg/cup to reach this urine concentration.
Some caffeine products are sold in very concentrated or pure forms. These products are a health concern. People can easily use these products in doses that are much too high by mistake. This can lead to death. As of 2018, the U.S. Food and Drug Administration (FDA) considers it unlawful for these products to be sold to consumers in bulk.

In foods, caffeine is used as an ingredient in soft drinks, energy drinks, and other beverages.
People with voice disorders, singers, and other voice professionals are often advised against using caffeine. However, until recently, this recommendation was based only on hearsay. Now developing research seems to indicate that caffeine may actually harm voice quality. But further study is necessary to confirm these early findings.

How does it work?

Caffeine works by stimulating the central nervous system (CNS), heart, muscles, and the centers that control blood pressure. Caffeine can raise blood pressure, but might not have this effect in people who use it all the time. Caffeine can also act like a “water pill” that increases urine flow. But again, it may not have this effect in people who use caffeine regularly. Also, drinking caffeine during moderate exercise is not likely to cause dehydration.

Uses & Effectiveness?

Likely Effective for

• Mental alertness. Research suggests that drinking caffeinated beverages throughout the day keeps the mind alert and might improve reaction times. Combining caffeine with glucose as an “energy drink” seems to improve mental performance better than either caffeine or glucose alone.

Possibly Effective for

• Decline in memory and thinking skills that occurs normally with age. Postmenopausal women who consume more than 175-371 mg of caffeine daily seem to have a lower risk of mental decline compared to those who consume less caffeine. There is some evidence that drinking caffeinated coffee but not caffeinated tea is linked to slower mental decline. But other research did not find a difference between caffeinated products.
• Asthma. Caffeine appears to improve airway function for up to 4 hours in people with asthma.
• Athletic performance. Taking caffeine seems to increase physical strength and endurance and might delay exhaustion during exercise. It might also reduce feelings of exertion and improve performance during activities such as cycling, running, playing soccer, and golfing. But caffeine doesn’t seem to improve performance during short-term, high-intensity exercise such as sprinting and lifting. The dose of caffeine doesn’t seem to impact its effect on athletic performance, but the timing might. Caffeine might work better during morning exercise than evening exercise. Also, taking caffeine daily for up to 4 weeks might also lead to tolerance. This might decrease or eliminate any performance enhancing effects of caffeine. The variability in the effects of caffeine might be due to genetic differences between people.
• Diabetes. Drinking beverages that contain caffeine is linked with a lower risk of developing type 2 diabetes. It appears that the more caffeine that is consumed, the lower the risk. Although caffeine might help prevent type 2 diabetes, it might not be effective in treating type 2 diabetes. Research on the effects of caffeine in people with type 1 diabetes is inconsistent. Some research shows benefit, while other research does not.
• Gallbladder disease. Drinking beverages that provide at least 400 mg of caffeine daily seems to reduce the risk of developing gallstone disease. The effect seems to be dose-dependent. Taking 800 mg of caffeine daily seems to work best.
• Swelling (inflammation) of the liver caused by the hepatitis C virus (hepatitis C). Research has found that higher intake of caffeine from coffee is linked with reduced liver scarring in people with hepatitis C.
• Low blood pressure. Drinking caffeinated beverages seems to increase blood pressure in older people with low blood pressure after eating.
• Memory. Taking 200 mg of caffeine by mouth daily seems to improve memory in some people with outgoing personalities and college students.
• Obesity. Taking caffeine in combination with ephedrine seems to help reduce weight, short-term. Taking 192 mg of caffeine in combination with 90 mg of ephedra daily for 6 months seems to cause a modest weight reduction (5.3 kg or about 12 pounds) in overweight people. This combination, along with limiting fat intake to 30 percent of calories and moderate exercise, also seems to reduce body fat, decrease “bad” low-density lipoprotein (LDL) cholesterol, and increase “good” high-density lipoprotein (HDL) cholesterol. However, there can be unwanted side effects. Even in carefully screened and monitored otherwise healthy adults, caffeine/ephedra combinations can cause changes in blood pressure and heart rate. Early research shows that taking a specific combination product (Prograde Metabolism) along with dieting reduces body weight and the size of the waist and hips.
• Pain. Research suggests that taking caffeine together with painkillers can reduce pain.
• Parkinson disease. Some research suggests that people who drink caffeinated beverages have a decreased risk of developing this condition. But this reduced risk is not observed in people who smoke cigarettes.
• Headache after epidural anesthesia. Taking caffeine by mouth or intravenously seems to help prevent headache after epidural anesthesia.
• Skin cancer. Research has found that higher intake of caffeine is linked with a reduced risk for developing a certain type of skin cancer, called non-melanoma skin cancer.

Possibly Ineffective for

• Irregular heartbeat (atrial fibrillation). Research suggests that taking caffeine during and after heart surgery does not reduce the risk for an irregular heart rhythm, called atrial fibrillation.
• Attention deficit-hyperactivity disorder (ADHD). Most research suggests that caffeine does not reduce ADHD symptoms in children. The use of caffeine in adolescents and adults with ADHD has not been studied.

More evidence is needed to rate caffeine for these uses.

Side Effects & Safety

When taken by mouth: Caffeine is LIKELY SAFE for most healthy adults when used in doses up to 400 mg per day. This amount of caffeine is similar to what is found in about 4 cups of coffee.

Caffeine is POSSIBLY UNSAFE when taken by mouth for a long time or in high doses (>400 mg per day). Caffeine can cause insomnia, nervousness and restlessness, stomach irritation, nausea and vomiting, increased heart rate and respiration, and other side effects. Caffeine can make sleep disorders in patients with acquired immunodeficiency syndrome (AIDS) worse. Larger doses might cause headache, anxiety, agitation, chest pain, and ringing in the ears.

Caffeine is LIKELY UNSAFE when taken by mouth in very high doses as it can cause irregular heartbeats and even death. Products with very concentrated or pure caffeine have a high risk of being used in doses that are too high. Avoid using these products.

Special Precautions & Warnings:

Children: Caffeine is POSSIBLY SAFE when given by mouth or intravenously (by IV) to preterm infants under the advice and care of a healthcare professional. Caffeine is also POSSIBLY SAFE when used by children and adolescents in amounts commonly found in foods.

Pregnancy and breast-feeding: Caffeine is POSSIBLY SAFE in pregnant or breast-feeding women when used daily amounts of less than 300 mg. This is about the amount in about 3 cups of coffee. Consuming larger amounts during pregnancy or when breast-feeding is POSSIBLY UNSAFE. When consumed in larger amounts during pregnancy, caffeine might increase the chance of miscarriage and other problems. Also, caffeine can pass into breast milk, so nursing mothers should closely monitor caffeine intake to make sure it is on the low side. High intake of caffeine by nursing mothers can cause sleep disturbances, irritability, and increased bowel activity in breast-fed infants.

Anxiety disorders: Caffeine might make these conditions worse. Use with care.

Bipolar disorder: Too much caffeine might make this condition worse. In one case, a 36-year-old man with controlled bipolar disorder was hospitalized with symptoms of mania after drinking several cans of an energy drink containing caffeine, taurine, inositol, and other ingredients (Red Bull Energy Drink) over a period of 4 days. Use caffeine with care and in low amounts if you have bipolar disorder.

Bleeding disorders: There is concern that caffeine might aggravate bleeding disorders. Use caffeine with care if you have a bleeding disorder.

Heart conditions: Caffeine can cause irregular heartbeat in sensitive people. Use caffeine with caution.

Diabetes: Some research suggests that caffeine may affect the way the body uses sugar and might worsen diabetes. However, the effect of caffeinated beverages and supplements has not been studied. If you have diabetes, use caffeine with caution.

Diarrhea: Caffeine, especially when taken in large amounts, might worsen diarrhea.

Epilepsy: People with epilepsy should avoid using caffeine in high doses. Low doses of caffeine should be used cautiously.

Glaucoma: Caffeine increases the pressure inside the eye. The increase occurs within 30 minutes and lasts for at least 90 minutes after drinking caffeinated beverages.

High blood pressure: Consuming caffeine might increase blood pressure in people with high blood pressure. However, this effect might be less in people who use caffeine regularly.

Loss of bladder control: Caffeine can make bladder control worse by increasing frequency of urination and the urge to urinate.

Irritable bowel syndrome (IBS): Caffeine, especially when taken in large amounts, might worsen diarrhea in people with IBS.

Weak bones (osteoporosis): Caffeine can increase the amount of calcium that is flushed out in the urine. If you have osteoporosis or low bone density, caffeine should be limited to less than 300 mg per day (approximately 2-3 cups of coffee). It is also a good idea to get extra calcium to make up for the amount that may be lost in the urine. If you are generally healthy and getting enough calcium from your food or supplements, taking up to 400 mg of caffeine per day (3-5 cups of coffee) doesn’t seem to increase the risk of getting osteoporosis. Older women with an inherited disorder that affects the way vitamin D is used should use caffeine with caution. Vitamin D works with calcium to build bones.

Parkinson disease: Taking caffeine with creatine might make Parkinson disease e get worse faster. If you have Parkinson disease and take creatine, use caffeine with caution.

Schizophrenia: Caffeine might worsen symptoms of schizophrenia.

 

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